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George Mason University
Job Opportunity

Scientist 1 at Genentech

Full Job Details

Employer: Genentech

Expires: 10/04/2026

Description We have a 1-year contract opening for a motivated Scientist 1 to join the Biochemical and Cellular Pharmacology (BCP) Department at Genentech's Research and Early Development (gRED) organization.The successful candidate will support small molecule drug discovery programs across therapeutic areas with a primary focus on oncology, working on therapeutics with novel mechanisms of action in the induced proximity space. This is an opportunity to contribute to cutting-edge science at the intersection of new modalities and drug discovery.The individual will assist in the development, optimization, and execution of in vitro biochemical and cellular assays to characterize and screen small molecule compounds. The role includes hands-on assay work, use of automation platforms, data analysis, documentation of results in laboratory notebooks and databases, and communicating results with scientists in the department. The candidate will work closely with BCP scientists and will have opportunities to interact with cross-functional project teams spanning medicinal chemistry, biology, and structural biology.Who You AreB.S. or M.S. in Biochemistry, Cell Biology, Chemistry, Pharmacology, Biology, or a related field1–4 years of laboratory experience in an academic or biotechnology settingHands-on experience with basic laboratory techniques (pipetting, microplate handling, reagent preparation)Foundational knowledge of biochemical or cellular assay principles — understanding how compounds are tested against biological systemsDemonstrated scientific curiosity and a strong motivation to learn new techniques and conceptsExcellent teamwork, communication, and organizational skillsWe encourage candidates from all backgrounds to apply. If you're excited about this role but your experience doesn't align perfectly with every listed qualification, we'd still like to hear from you. Additional Desirable SkillsExperience with microplate-based assay formats (e.g., TR-FRET, NanoBRET, luminescence, or fluorescence-based readouts)Experience with cell-based assays, including cell culture and cell viability measurementsExposure to laboratory automation or semi-automated liquid handling platformsExperience testing the effects of small molecules or other agents on biochemical or cellular systemsComfort with data analysis and visualization tools (e.g., GraphPad Prism, Excel)Strong attention to consistency and reproducibility in routine assay executionWhy This RoleWork at the forefront of drug discovery in induced proximity, an exciting emerging modalityContribute to drug discovery programs with real translational impact, primarily in oncologyGain experience in a department that is a leader in automation and assay technologiesInteract with cross-functional project teams and broaden your scientific exposure

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