Gutting’s primary research interest is aimed at developing better risk assessments for bioterrorism agents (bacterial and viral agents, as well as protein toxins).  Assessing the risk of adverse health events following exposure to any toxic agent requires knowledge of the mechanisms associated with the pathogenesis, the ability to characterize key interactions quantitatively, and the computational tools required to extrapolate dose-response data from the lab to the real world.  Most of his bench work involves research on host-pathogen interactions using relevant in vitro and in vivo models, with a particular focus on immune responses.  Computationally, his research involves working with numerous types of models: empirical, stochastic and deterministic modeling.  In additional to risk assessment, Dr. Gutting also has an active research program investigating the use of human wearable biomonitors for exposure surveillance.