Joel Schnur
- Research Profressor Bio/Molecular Science
Contact Info
- Name
- Joel Schnur
- Job Title
- Research Profressor Bio/Molecular Science
- Phone Number
- Office Number
- 3103 Exploratory Hall MSN 5C3Office Hours: Wed 10:30 a.m. to 2:30 p.m.
Affiliations
Departments
- Dean's Administration (Research Faculty)
Other Affiliations
- Mason Science Bio/Molecular Science
Centers
- Center for Drug Discovery for Rare Diseases
Research Areas
- Cross Disciplinary Bio/Chem/Physics
About
When I was director of the Center for Bio/Molecular Science and Engineering (Code 6900), I provided scientific direction and management in the areas of complex bio/molecular systems with the aim of modifying structures in ways that led to the development of useful devices, techniques and systems of use for the Navy, DoD, and the US.. Through my leadership the initial small group that was formed in the spring of 1983 has grown to a branch (6190 -1984) and in 1991 to the division level NRL Center for Bio/Molecular Science and Engineering (code 6900). As Director I provided strong and creative scientific and administrative leadership in the application of the tools of advanced biology to the solution of complex material problems faced by the modern Navy, DOD, and the U.S. I have pioneered the concept of “biotechnology beyond medicine” in the early late 1970’s and early 1980s. This emerging area has now been adopted by the world community and is leading to many significant technological breakthroughs for both commercial and DOD applications.
I have also led the way for the DOD in the development of dual use technology through the use of Cooperative Research Agreements and associated licensing agreements. My research in self-assembly, Nanotechnology, and advanced bio diagnostics has led to the licensing of many of my patents in micro lithography, controlled release , resequencing, as well as one of the first CRADA's in the NAVY at NRL with Shipley Co in Newton Mass (>$10,000,000). My research interests focus on understanding the relationship between the structure of molecules and observed macroscopic phenomena. This interest has led him to on critical phenomena, liquid crystals, picosecond spectroscopy, high pressure and shock related phenomena, and self-assembly of biologically derived microstructures. By working in these areas I developed a keen appreciation of the importance of interdisciplinary research.
After retiring from the NRL I took as position as Research Professor, Bio/Molecular Science in the College of Science. In this position I actively mentor tenure track faculty (over 60 in the past 11 years) as well as pursuing my research. My recent work has focused on the applications of emerging technologies to problems of medical significance. See for example Discovery of Novel Antimicrobial Peptides from Varanus komodoensis (Komodo Dragon) by Large-Scale Analyses andDe-Novo-Assisted Sequencing Using Electron-Transfer Dissociation Mass Spectrometry, Journal of Proteome Research, B. Bishop et al., Feb. 2017
Selected Publications
Most of my early work involved self-assembly. I became very interested in the ways that lipids could self-assemble into interesting structures. The role of chirality in the process fascinated me. Highlights of that work is show below. Selected Publications below (A comprehensive list may be found Google Scholar):
"Lipid Tubules: A Paradigm for Molecularly Engineering Structures," J.M. Schnur, Science, 262:1669-1676 (1993)
"Diacetylenic Lipid Tubules: Experimental Evidence for a Chiral Molecular Architecture," J.M. Schnur, *B.R. Ratna, J.V. Selinger, A. Singh, G. Jyothi, K..K. Easwaran, Science, Vol. 264, pp. 945-947, 13 May 1994.
"Chiral Molecular Self-Assembly of Phospholipid Tubules: A Circular Dichroism Study," Mark S. Spector, Kalpathy R.K. Easwaran, Ghanta Jyothi, Jonathan V. Selinger, Alok Singh and Joel M. Schnur, Proceedings National Academy of Science, Vol. 93, pp. 12943-12946, November 1996.
"DNA Ordering on a Lipid Membrane," Mark S. Spector and Joel M. Schnur, Science, 7 February 1997, Volume 275, pp. 791-792.
I have also been interested in a number of topics including resequencing and bio-based energy transfer. Four of the energy transfer papers are shown below:
Nikolai Lebedev, Scott A. Trammell, Stanislav Tsoi, Anthony Spano, Jin Ho Kim, Jimmy Xu, Mark E. Twigg, and Joel M. Schnur: Increasing Efficiency of Photoelectronic Conversion by Encapsulation of Photosynthetic Reaction Center Proteins in Arrayed Carbon Nanotube Electrode. - Langmuir, 24(16):8871-8876, (2008).
Scott A. Trammell, Igor Griva, Anthony Spano, Stanislav Tsoi, Leonard M. Tender, Joel Schnur, and Nikolai Lebedev: Effects of Distance and Driving Force on Photoinduced Electron Transfer between Photosynthetic Reaction Centers and Gold Electrodes. – Journal of Physical Chemistry-C, 111:17122-17130, (2007)
Anthony J. Spano, Frank S. Chen, Benjamin E. Goodman, Agnes E. Sabat, Martha N. Simon, Joseph S. Wall, John J. Correia, Wilson McIvor, William W. Newcomb, Jay C. Brown, Joel M. Schnur, Nikolai Lebedev: In vitro assembly of a prohead-like structure of the Rhodobacter capsulatus gene transfer agent”, Virology 364:95–102, 2007
Nikolai Lebedev,*† Scott A. Trammell,† Anthony Spano,‡ Evgeny Lukashev,‡§ Igor Griva, and Joel Schnur, “Conductive wiring of immobilized photosynthetic Reaction Center to electrode by Cytochrome c", Journal of the American chemical Society J. AM. CHEM. SOC. 9 VOL. 128, NO. 37, 12045, 2006
Awards
1992 AT&T Bell Laboratories Scientist of the Year Award
1993 Superior Civilian Service Award
2001 Presidential Rank Award
2005 Presidential Rank Award
2006 Top Navy Scientist Award
2009 Federal Laboratory Technology Transfer Award
Contact Info
- Name
- Joel Schnur
- Job Title
- Research Profressor Bio/Molecular Science
- Phone Number
- Office Number
- 3103 Exploratory Hall MSN 5C3Office Hours: Wed 10:30 a.m. to 2:30 p.m.