Faculty & Staff Directory
Rosa Isela Gallagher
- Senior Research Scientist
Contact Info
- Name
- Rosa Isela Gallagher
- Job Title
- Senior Research Scientist
- Phone Number
- Office Number
- Applied Proteomics and Molecular Medicine Institute for Advanced Biomedical Research, Office 2009 SciTech, MSN: 1A9
Affiliations
Centers
- Center for Applied Proteomics and Molecular Medicine (CAPMM)
Research Areas
- Biomedical Research
- Proteomics
- Systems Biology
Education
PhD in Biosciences for Cell and Molecular Biology, George Mason University (2019)
About
Dr. Gallagher's research incorporates Laser Capture Microdissection (LCM), Reverse Phase Protein Microarray (RPPA) technology and immunohistochemistry (IHC) to investigate unique signaling pathway profiles in cancer tissue that can be utilized for diagnosis, prognosis, targeted therapeutics and individualized therapy.
Current Research
Dr. Gallagher’s current research focuses on the proteomic profiling of solid tumor tissues, including breast, thyroid, lung, and prostate for designing personalized therapeutic strategies, and identification of functional signaling pathways underlying resistance to targeted therapies.
Selected Publications
- Olshen A, Wolf D, Jones EF, Newitt D, van’t Veer L, Yau C, Esserman L, Wulfkuhle JD, Gallagher RI, Singer L, Petricoin EF, Hylton IIIN, Park CC. 2018. Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL. J. Med. Img. 5(1): 011014.
- Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, Bae YK, Wulfkuhle JD, Gallagher RI, Petricoin EF, et al. 2017. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chem Biol. 19;24(10):1314.
- Jayappa KD, Portell CA, Gordon VL, Capaldo BJ, Bekiranov S, Axelrod MJ, Brett LK, Wulfkuhle JD, Gallagher RI, Petricoin EF, Bender TP, Williams ME, Weber MJ. 2017. Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL. Blood Adv. 1(14):933-94.
- Pierobon M, Ramos C, Wong S, Hodge KA, Aldrich J, Byron S, Anthony SP, Robert NJ, Northfelt DW, Jahanzeb M, Vocila L, Wulfkuhle J, Gambara G, Gallagher RI, Dunetz B, Hoke N, Dong T, Craig DW, Cristofanilli M, Leyland-Jones B, Liotta LA, O'Shaughnessy JA, Carpten JD, Petricoin EF. 2017. Enrichment of PI3K-AKT-mTOR Pathway Activation in Hepatic Metastases from Breast Cancer. Clin Cancer Res. 23(16):4919-4928.
- Gallagher RI, Espina V. 2014. Reverse phase protein arrays: mapping the path towards personalized medicine. Mol Diagn Ther. 18(6):619-30.
Contact Info
- Name
- Rosa Isela Gallagher
- Job Title
- Senior Research Scientist
- Phone Number
- Office Number
- Applied Proteomics and Molecular Medicine Institute for Advanced Biomedical Research, Office 2009 SciTech, MSN: 1A9