Faculty & Staff Directory
- Research Associate Professor
Postdoctoral Research, Ludwig Institute for Cancer Research, University of California at San Diego (2002-2005)
PhD, Biochemistry and Biophysics, University of Illinois at Urbana-Champaign (2002)
MS, Biochemistry and Cell Biology, Nankai University (1995)
BS, Nankai University (1992)
Our mass spectrometry lab is equipped with state-of-the-art mass spectrometers. My research is focused on biomarker discovery relevant to cancers and other diseases from serum, tissue and body fluids, using advanced liquid chromatography coupled nano-electrospray tandem mass spectrometry technique. I also collaborate with other researchers to develop effective mass spectrometry methods for protein identification and post-translational modification characterization.
Barrera MD, Callahan V, Akhrymuk I, Bhalla N, Zhou W, Campbell C, Narayanan A, Kehn-Hall K. Proteomic Discovery of VEEV E2-host partner interactions identifies GRP78 inhibitor HA15 as a potential therapeutic for alphavirus infections. Pathogens 2021, 10, 283. 2021 Mar 2;10(3):283. PMCID:PMC8000471.
Fredolini C, Pathak KV, Paris L, Chapple KM, Tsantilas KA, Rosenow M, Tegeler TJ, Garcia-Mansfield K, Tamburro D, Zhou W, Russo P, Massarut S, Facchiano F, Belluco C, De Maria R, Garaci E, Liotta L, Petricoin EF, Pirrotte P. Shotgun proteomics coupled to nanoparticle-based biomarker enrichment reveals a novel panel of extracellular matrix proteins as candidate serum protein biomarkers for early-stage breast cancer detection. Breast Cancer Res. 2020 Dec 2;22(1):135. PMCID:PMC7709252.
Magni R, Almofee R, Yusuf S, Mueller C, Vuong N, Almosuli M, Hoang M, Meade K, Sethi I, Mohammed N, Araujo R, McDonald T, Marcelli P, Espina V, Kim B, Garritsen A, Green C, Russo P, Zhou W, Vaisman I, Petricoin E, Hoadley D, Molestina R, McIntyre H, Liotta L, Luchini A. Evaluation of pathogen specific urinary peptides in tick-borne illnesses. Sci Rep. 2020 Nov 9;10(1):19340. PMCID:PMC7653918.
Bakovic A, Bhalla N, Kortchak S, Sun C, Zhou W, Ahmed A, Risner K, Klimstra WB, Narayanan A. Venezuelan equine encephalitis virus nsP3 phosphorylation can be mediated by IKKβ kinase activity and abrogation of phosphorylation inhibits negative-strand synthesis. Viruses 2020, 12, 1021. PMCID:PMC7551587.
Mohammed SI, Torres-Luquis O, Zhou W, Lanman NA, Espina V, Liotta L. Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis. Breast Cancer (Dove Med Press), 2020 Mar 25;12:57-67. doi: 10.2147/BCTT.S236168. eCollection 2020. PMCID:PMC7104086.