Petricoin Conducting Protein Pathway Activation Mapping Of Tissue Cells Treated With Molecular Inhibitors

Emanuel Petricoin, Professor, School of Systems Biology and Co-Director, Center for Applied Proteomics and Molecular Medicine (CAPMM), received funding from the University of North Carolina at Chapel Hill for the project: "Protein pathway activation mapping of tissue cells treated with molecular inhibitors."  

For this project, Petricoin will receive cell culture tissue cells and cell lysates from UNC/Springworks Therapeutics, Inc. CAPMM researchers will perform all aspects of the Reverse Phase Protein Array (RPPA) analysis including lysing, plating, printing, staining, imaging, and data extraction and analysis. Mason researchers will share RPPA data with UNC/Springworks Therapeutics, Inc. and jointly analyze it. 

Petricoin received $31,780 from the University of North Carolina at Chapel Hill for this project. Funding began in July 2021 and will end in July 2022.