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Genetic science research

Recent Publications of Dr. Fatah Kashanchi

Khatkar P, Mensah G, Ning S, et al. HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules. Pharmaceuticals (Basel). 2023;17(1):33. Published 2023 Dec 25. doi:10.3390/ph17010033. https://www.mdpi.com/1424-8247/17/1/33

 

Williams A, Khatkar P, Branscome H, et al. The Use of CBD and Its Synthetic Analog HU308 in HIV-1-Infected Myeloid Cells. Pharmaceuticals (Basel). 2023;16(8):1147. Published 2023 Aug 12. doi:10.3390/ph16081147. https://pubmed.ncbi.nlm.nih.gov/37631062/

 

DeMarino, C., Cowen, M., Khatkar, P., Cotto, B., Branscome, H., Kim, Y., Sharif, S. A., Agbottah, E. T., Zhou, W., Costiniuk, C. T., Jenabian, M. A., Gelber, C., Liotta, L. A., Langford, D., & Kashanchi, F. (2022). Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription. Cells, 11(4), 723. https://doi.org/10.3390/cells11040723

 

Branscome, H., Khatkar, P., Al Sharif, S., Yin, D., Jacob, S., Cowen, M., Kim, Y., Erickson, J., Brantner, C. A., El-Hage, N., Liotta, L. A., & Kashanchi, F. (2022). Retroviral infection of human neurospheres and use of stem Cell EVs to repair cellular damage. Scientific reports, 12(1), 2019. https://doi.org/10.1038/s41598-022-05848-x

 

Williams A, Branscome H, Khatkar P, Mensah GA, Al Sharif S, Pinto DO, DeMarino C, Kashanchi F. A comprehensive review of COVID-19 biology, diagnostics, therapeutics, and disease impacting the central nervous system.
J Neurovirol. 2021 Oct;27(5):667-690. doi: 10.1007/s13365-021-00998-6. Epub 2021 Sep 28.
Link: https://pubmed.ncbi.nlm.nih.gov/34581996/

 

Kim Y, Mensah GA, Al Sharif S, Pinto DO, Branscome H, Yelamanchili SV, Cowen M, Erickson J, Khatkar P, Mahieux R, Kashanchi F. Extracellular Vesicles from Infected Cells Are Released Prior to Virion Release.  Cells. 2021 Apr 1;10(4):781. doi: 10.3390/cells10040781.
Link: https://pubmed.ncbi.nlm.nih.gov/33916140/

 

Pinto DO, Al Sharif S, Mensah G, Cowen M, Khatkar P, Erickson J, Branscome H, Lattanze T, DeMarino C, Alem F, Magni R, Zhou W, Alais S, Dutartre H, El-Hage N, Mahieux R, Liotta LA, Kashanchi F. Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread. Retrovirology. 2021 Feb 23;18(1):6. doi: 10.1186/s12977-021-00550-8.
Link: https://pubmed.ncbi.nlm.nih.gov/33622348/

 

Al Sharif S, Pinto DO, Mensah GA, Dehbandi F, Khatkar P, Kim Y, Branscome H, Kashanchi F. Extracellular Vesicles in HTLV-1 Communication: The Story of an Invisible Messenger.
Viruses. 2020 Dec 10;12(12):1422. doi: 10.3390/v12121422.
Link: https://pubmed.ncbi.nlm.nih.gov/33322043/

 

Sampey GC, Iordanskiy S, Pleet ML, DeMarino C, Romerio F, Mahieux R, Kashanchi F.  Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals. Viruses. 2020 Sep 23;12(10):1067. doi: 10.3390/v12101067.
Link: https://pubmed.ncbi.nlm.nih.gov/32977702/

 

Pinto DO, DeMarino C, Vo TT, Cowen M, Kim Y, Pleet ML, Barclay RA, Noren Hooten N, Evans MK, Heredia A, Batrakova EV, Iordanskiy S, Kashanchi F. Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors. Viruses. 2020 Aug 13;12(8):885. doi: 10.3390/v12080885.
Link: https://pubmed.ncbi.nlm.nih.gov/32823598/

 

Branscome H, Paul S, Yin D, El-Hage N, Agbottah ET, Zadeh MA, Liotta LA, Kashanchi F. Use of Stem Cell Extracellular Vesicles as a "Holistic" Approach to CNS Repair. Front Cell Dev Biol. 2020 Jun 10;8:455. doi: 10.3389/fcell.2020.00455. eCollection 2020
Link: https://www.frontiersin.org/articles/10.3389/fcell.2020.00455/full

 

Barclay RA, Mensah GA, Cowen M, DeMarino C, Kim Y, Pinto DO, Erickson J, Kashanchi F. Extracellular Vesicle Activation of Latent HIV-1 Is Driven by EV-Associated c-Src and Cellular SRC-1 via the PI3K/AKT/mTOR Pathway. Viruses. 2020 Jun 19;12(6):E665. doi: 10.3390/v12060665.
Link: https://www.mdpi.com/1999-4915/12/6/665

 

DeMarino C, Cowen M, Pleet ML, Pinto DO, Khatkar P, Erickson J, Docken SS, Russell N, Reichmuth B, Phan T, Kuang Y, Anderson DM, Emelianenko M, Kashanchi F. Differences in Transcriptional Dynamics Between T-cells and Macrophages as Determined by a Three-State Mathematical Model. Sci Rep. 2020 Feb 10;10(1):2227. doi: 10.1038/s41598-020-59008-0.
Link: https://www.nature.com/articles/s41598-020-59008-0