Upcoming Events
CAGS: Deep neural networks and DNA variant effect predictions in humans
Dec 3, 2021, 12:30 - 1:30 PM
Speaker: Ágúst Egilsson, NATERA Inc.
Title: Deep neural networks and DNA variant effect predictions in humans
Abstract:
In this applied session we will discuss emerging approaches that rely on the generalizability and explainability of deep neural networks for understanding genomic variants and DNA regulatory activity in the non-coding regions of the human genome. Currently, these approaches rely on the use of convolutions or transformers and variational autoencoders and are achieving state-of-the-art performance comparable to experimental results in some use cases. During the talk we will detail the network structures and explore the recent history of the approaches. Keywords: Deep neural networks, convolutions, transformers, multi head attention, autoencoders, DNA, genome, variant classification.
Time: Friday, December 3, 2021, 12:30pm – 1:30pm
