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Genetic science research
George Mason University

Faculty & Staff Directory

Nadine Kabbani

  • Associate Professor
  • Associate Chair for Research, Interdisciplinary Program in Neuroscience

    Contact Info

    Kabbani Photo
    Name
    Dr. Nadine Kabbani
    Job Title
    Associate Professor
    Associate Chair for Research, Interdisciplinary Program in Neuroscience
    Phone Number
    703-993-4406
    Office Number
    Krasnow Institute, Room 233, MSN 2A1

    Affiliations

    Departments

    Other Affiliations

    • Schar School for Policy and Government
    • Center for Biomedical Science and Policy

    Centers

    • Institute for Biohealth Innovation

    Research Areas

    • Neuroscience
    • Pharmacology
    • Science Policy

    Education

    PhD, Pharmacology, Penn State College of Medicine, (2003)

    BS, George Mason University, (1997)

    About

    I am interested in cell signaling as an adaptive evolutionary biological process and in receptor signaling as a specific paradigm of information flow in the cell. I study mechanisms of signaling through protein interactions and signaling networks within cells. A key line of work focuses on nicotinic acetylcholine receptors, which are key molecular targets for treating human diseases such as schizophrenia and Alzheimer’s Disease.

    My lab uses a range of scientific techniques from molecular biology to functional imaging, proteomic, and bioinformatic platforms. Our publications highlight the use of complementary techniques, innovative ideas, and the ability to “think outside the box” whenever possible.

    I am an affiliate of the Schar School for Policy and Government and interested in specific areas of convergence between science and policy as they relate to emerging environmental, chemical, and human health threats. Current projects include studies on the interaction between environmental toxins such as cyanotoxins and pesticides and public health.

     

    Teaching Focus

    Cellular and Molecular Neuroscience, Neuropharmacology, Neuroscience and Society

    Selected Publications

    Google Scholar: https://scholar.google.com/citations?user=Aip4aXEAAAAJ&hl=en

    W. Huang, N. Kabbani, T. K. Brannan, M. K. Lin, M. M. Theiss, J. F. Hamilton, J. M. Ecklund, Y. P. Conley, Y. Vodovotz, D. Brienza, A. K. Wagner, E. Robbins, G. A. Sowa, R. H. Lipsky. Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury. J Neurotrauma. 2019, 36(21):3026-3033

    N. Kabbani, J. L Olds. Does COVID19 Infect the Brain? If So, Smokers Might Be at a Higher Risk. Mol Pharmacol. 2020, 97(5):351-353.

    N. Kabbani and J. Olds.  Nicotinic receptor targeting in physiological and environmental vulnerability: A whole of biosphere perspective. Sci Total Environ 2021; 780:146642.

    P. Sinclair, N. Kabbani. Differential Proteomic Analysis of Amyloid Beta 42 Toxicity in the Human Neural SH-SY5Y Cell Line Reveals Mechanisms of Alpha 7 Nicotinic Receptor Involvement. PLoS One 2022; 17(8):e0270479.

    RJ Wickham, BJ Henderson, AB Jackson, N. Kabbani. Pharmacological and behavioral effects of added flavorants on tobacco addiction. Front Neurosci. 2022 16:1100476.

    Contact Info

    Kabbani Photo
    Name
    Dr. Nadine Kabbani
    Job Title
    Associate Professor
    Associate Chair for Research, Interdisciplinary Program in Neuroscience
    Phone Number
    703-993-4406
    Office Number
    Krasnow Institute, Room 233, MSN 2A1