Faculty & Staff Directory
Ancha Baranova
- Professor
Contact Info
- Name
- Dr. Ancha Baranova
- Job Title
- Professor
- Website
- Phone Number
- Office Number
- Colgan Hall, Room 312G
Affiliations
Departments
- School of Systems Biology (Research Faculty)
- School of Systems Biology (Instructional Faculty)
- Neuroscience Program (Research Faculty)
- Neuroscience Program (Instructional Faculty)
Centers
- Chronic Metabolic and Rare Diseases Systems Biology Initiative (ChroMe RaDSBIn)
- Institute for Biohealth Innovation
Research Areas
- Applied Science
- Bio-health/Health
- Biology
- Biomedical Research
- Healthcare Technology
- Neuroscience
- Personalized Medicine
- Pre-Med
- Systems Biology
Education
DSci in Genetics, Institute of General Genetics Russian Academy of Science, (2004). PhD in Molecular Biology/Virology, Lomonosov Moscow State University, Moscow, Russia (1998). MS in Biochemistry, Lomonosov
About
The strongest aspect of my research program lies in its transdisciplinary nature. In over more than twenty years of active time in academia, I have developed an expertise in a variety of research fields. In many collaborations, I analyze multidimensional datasets and make sense out of this data, putting together arrays of disparate data pieces and generating testable hypotheses ready for experimental validation. With that, we are constantly building the forest out of individual trees.
My lab has discovered many biomarkers for chronic liver diseases, cancer and other illnesses, a biosynthesis of the melanin in human adipose, two novel properties of cell-free DNA, and a variety of novel functions for known biomolecules. Recently, my lab has entered a field of anti-aging research. We dissect major pathophysiological components of aging, namely systemic inflammation, insulin resistance, and organ fibrosis. Our work in personalized medicine has a particular emphasis on longitudinal monitoring and management of health in pre-symptomatic individuals, and augmenting the body’s homeostasis by non-pharmacological means.
Director, MS in Biology program
Director, Certificate in Personalized medicine
Director for the Chronic Metabolic and Rare Diseases Systems Biology Initiative (ChroMe RaDSBIn)
Current Research
Dissection of molecular networks underpinning common human illnesses.
Teaching Focus
Human Genetics, Cancer Biology, Biotechnology, Research and Development in Biotechnologucal Company, Longevity and Healthspan
Selected Publications
1: Baranova A, Maltseva D, Tonevitsky A. Adipose may actively delay progression of NAFLD by releasing tumor-suppressing, anti-fibrotic miR-122 into circulation. Obes Rev. 2019 Jan;20(1):108-118. doi: 10.1111/obr.12765. PubMed PMID: 30248223.
2: Marakasova ES, Eisenhaber B, Maurer-Stroh S, Eisenhaber F, Baranova A.
Prenylation of viral proteins by enzymes of the host: Virus-driven rationale for
therapy with statins and FT/GGT1 inhibitors. Bioessays. 2017 Oct;39(10). doi:
10.1002/bies.201700014. PubMed PMID: 28885709.
3: Kural KC, Tandon N, Skoblov M, Kel-Margoulis OV, Baranova AV. Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. BMC Genomics. 2016 Dec 28;17(Suppl 14):1030. doi: 10.1186/s12864-016-3352-4. PubMed PMID: 28105936; PubMed Central PMCID: PMC5249001.
4: Baranova A, Willett JD. Anti-aging dilemma: to restore the hardware or to
reinstall the software? Front Genet. 2015 Apr 14;6:129. doi: 10.3389/fgene.2015.00129. PubMed PMID: 25926845; PubMed Central
PMCID: PMC4396409.
5:Glebova K, Veiko N, Kostyuk S, Izhevskaya V, Baranova A. Oxidized extracellular DNA as a stress signal that may modify response to anticancer therapy. Cancer Lett. 2015 Jan 1;356(1):22-33. doi: 10.1016/j.canlet.2013.09.005. PubMed PMID: 24045040.
Awards
COS Publication Awards 2013 and 2011
Contact Info
- Name
- Dr. Ancha Baranova
- Job Title
- Professor
- Website
- Phone Number
- Office Number
- Colgan Hall, Room 312G